Considering the role of knowledge sharing in increasing the effectiveness and productivity of organizations, the research aimed to identify the effect of organizational trust and spirituality in the work environment on the behavior of knowledge sharing in Islamic Management Jurisprudence Foundation in Qom. A sample of 100 employees and experts of Islamic Management Jurisprudence Foundation in Qom was selected using random sampling and questionnaires of organizational trust, knowledge sharing behavior and spirituality in the workplace were distributed among them. Data analysis and identification of causal relationships between variables were done using structural equations based on Smart PLS software (version 3). The findings showed that spirituality in the work environment and organizational trust have a positive and meaningful effect on the knowledge sharing behavior of employees of the Islamic Management Jurisprudence Foundation. Also, the findings showed that these two variables predict a total of 50% of the changes in the knowledge sharing behavior variable. According to the findings, it is suggested that managers and officials of Islamic Management Jurisprudence Foundation, in order to share and share knowledge in the organizational environment, push the culture of the organization as much as possible towards increasing trust and spirituality in the work environment among the employees and the organizational environment. .